“Dogs can be trained to identify the scent of lung cancer long before symptoms develop,” the Daily Mail has today reported. The newspaper said that “sniffer dogs can be relied upon to find the unique smell of the disease in seven out of 10 sufferers”.The claim is based on a study that had trained four dogs to detect breath samples from people with lung cancer among those taken from healthy people and people with the lung condition COPD. The researchers determined that when three out of the four dogs agreed on which samples indicated lung cancer then this consensus could correctly detect a cancer sample 72% of the time. The dogs could also correctly rule out cancer in healthy samples 94% of the time. However, the researchers point out that the dogs may have been detecting the medication used by the cancer patients rather than substances indicating the disease itself. This casts doubt on how well the technique might detect undiagnosed cancer. The accuracy of the … [Read more...] about Can dogs sniff out lung cancer?
Treatment non small cell lung cancer
LUNG cancer is the second most common type of the disease in the UK - with 43,500 people diagnosed with the condition each year. A lingering cough, feeling tired and losing your appetite could be mistaken for a virus or even a common cold. How common is lung cancer? Primary lung cancer - which begins in the lungs, rather than spreading to them from another place - is the second most common type of cancer in Britain. There are two types of lung cancer - 80 per cent of cases are non-small-cell, while small-cell lung cancer is a rarer type which spreads more quickly. It is almost equally common in women and men, but it's rare in people under the age of 40. NHS guidelines state rates of lung cancer increase rapidly with age, and it's most common in people aged 70-74. What are the eight key signs and symptoms of lung cancer? Symptoms of lung cancer can include: Having a cough most of the time A change in a cough you have had for a long time Being short of breath … [Read more...] about The 8 ‘red flag’ signs of lung cancer you should NEVER ignore
AstraZeneca’s new oncology drug Imfinzi has had further success after clinical trials showed it helps lung cancer patients live longer. The good news follows a trial in May last year in which people with the inoperable stage III non-small cell lung cancer lived on average 16.8 months without their disease worsening (known as "progression-free survival" in the industry) compared with 5.6 months for those on the placebo. That led to the drug winning approval from US an Canadian regulators earlier this year. It is still under review by the European Medicines Agency. Imfinzi is part of a new generation of cancer drugs in the growing field of immuno-oncology. It is an antibody, or protein, that tackles tumours by blocking the mechanism they use to evade detection by the body’s own immune system. It is already being used to treat people with late-stage bladder cancer, but lung cancer is perhaps the more important disease from a purely financial perspective, given that it is … [Read more...] about Success for AstraZeneca after lung cancer treatment improves survival
AstraZeneca's share price took a slight dip this morning after it revealed a phase three trial of a potential treatment for lung cancer had been unsuccessful. The pharmaceutical giant, which is in the process of moving its global headquarters to Cambridge, had been testing a combination of two drugs, Imfinzi and tremelimumab, on patients with patients with locally-advanced or metastatic non-small cell lung cancer who have received at least two prior treatments. But the results of the trial, named ARCTIC, show it didn't produce a clinically-meaningful improvement in terms progression-free survival and overall survival for patients when compared to the current standard treatment. However, it wasn't all bad news, as Imfinzi used as a monotherapy was shown to reduce the risk of death when compared to chemotherapy. Sean Bohen, executive vice president, global medicines development and chief medical officer for AstraZeneca, said: "While we are disappointed that the combination of Imfinzi … [Read more...] about AstraZeneca suffers lung cancer set-back
Bristol-Myers Squibb Co.’s drug cocktail for lung cancer patients with highly mutated tumors met a major goal of a late-stage study, an important step as the company tries to get the therapy used in newly diagnosed patients.In the 299-patient trial, patients with advanced lung cancer who got a combination of Bristol-Myers’ drugs Yervoy and Opdivo were 42 percent less likely to have their disease progress, compared to patients on chemotherapy alone, according to data presented at the American Association for Cancer Research meeting in Chicago. Bristol-Myers said in February that the trial succeeded, but didn’t provide specifics.For Bristol-Myers, the results validate a change the company made midway through the trial, a move that prompted some skeptics to question whether Bristol-Myers was altering the trial to try and create a better result. Instead of a measure Bristol-Myers had used in past trials, it decided to target patients whose tumors have high levels of … [Read more...] about Bristol-Myers Says Lung Cancer Drug Combination Met Trial Goal