Police were led to a massive cannabis farm in a disused nightclub after a tip-off from members of the public.
Cheshire Police said the force had arrested two 16-year-old boys and a 27-year-old man on suspicion of production of cannabis.
The suspects have since been released under investigation.
In February 2015 a similar operation was found in the building that once housed Club Wired, in Mersey Street.
At least 1,600 plants were discovered by officers with an estimated street value of £1.5million and a potential annual yield of up to £6milion.
Three Vietnamese men, Hong Tran, Tuan Phan and Le Truong, were jailed for a combined 40 years for production of cannabis after telling a court they had travelled to to the UK on the promise of a better life.
All three men were set to be deported after the completion of their sentences.
Anyone with information on the Eivissa incident is urged to contact Cheshire Police on 101, quoting incident number IML429647, or to call Crimestoppers anonymously on 0800 555 111.
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